The Status of Plasma Homocysteine in Healthy-Looking Elderly Men and Its Link to Postprandial Glucose Level

Document Type : Original Article

Authors

1 Community Health Department, Technical Institute of Baquba, Middle Technical University, Diyala, Iraq.

2 Middle Technical University, Technical College /Baquba, Department of Medical laboratory Techniques, Diyala, Iraq

Abstract

Objective: The study aimed to examine the plasma homocysteine levels in a population of non-diabetic elderly individuals and investigate their potential association with postprandial glucose levels. Materials and methods: A sample of 70 volunteer elderly retired men aged 63–79 who are attending outpatient clinics after a clinical examination is sent to the laboratory technician to conduct a homocysteine test and postprandial glucose test. After obtaining results, the data were entered and then analyzed using the SPSS program (Version 21) to summarize the results into graphics and tables. The t-test was used to analyze these data, where 0.05 was the minimum significance level. Results: The results of the study showed that 60% of healthy elderly people showed a rise in the level of plasma homocysteine, particularly among those over 70 years old. Also, the mean level of fasting glucose (10.93 mmol/l) was higher in non-diabetic elderly people who were affected by hyperhomocysteinemia. In conclusion, hyperhomocysteinemia, a condition affecting older individuals, is physiologically linked to increased plasma glucose levels, particularly in those over 70 years old.

Keywords