The correlation between circulating antigen in urine and the intensity of Schistosoma haematobium infection

Document Type : Original Article

Author

Society of Pathological biochemistry and hematology

Abstract

Background: There are two methods for diagnosis of schistosomiasis, parasitological(microscopic detection of eggs), and/or immunological methods (antibody and antigen detection), due to the decreasing and elimination of Schistosomiasis infection in many countries, detection of Antigen is more valuable for active infection detection,Schistosome antigens are present in serum and urine of infected subjects.Subjects and methods: This study is a cross-sectional study designed to study the relation between a commercially available kit, using circulating antigen in urine and the intensity of infection of S.haematobium detected by microscopic examination in urine, in the study population, this performed on 50 positive S.haematobium samples and 50 negative samples for individuals matching in age and gender, in addition, urine microscopic examination was done for detection of S.haematobium eggs by sedimentation centrifugation and nuclepore filteration techniques. Results:  The results showed that the Schistosoma haematobium infection as detected by the Circulating antigen in urine related to the intensity of infection detected by parasitologic techniques. In light cases, it detected 54.5 %, and in heavy cases, it increased to 66.7 %, While, P-value is 0.575 not significant at p < 0.05

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